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Dual medication regimen may improve blood pressure in patients with type 1 diabetes or type 2 diabetes

Individuals who have type 1 diabetes or type 2 diabetes may require extensive drug regimens in order to control their blood sugar levels and treat other symptoms they may have.

In particular, those who developed type 2 diabetes due to long-term obesity may have coexisting risk factors for cardiovascular complications, such as high blood pressure or elevated triglyceride levels.

However, a recent article published by Renal and Urology News indicated that a combination of two blood pressure medications may be more effective than using a single drug to treat hypertension in patients with type 1 diabetes or type 2 diabetes.



The research involved more than 450 participants who were over the age of 55 and had a mean sitting systolic blood pressure between 160 mmHg and 200 mmHg. One group was provided with a drug called hydrochlorothiazide (HCTZ), which had previously been shown to help lower blood pressure, while another subset received a combination of aliskiren and HCTZ, the news provider reported.

Four weeks later, the study's results showed that the mean decrease in systolic blood pressure was nearly 28 mmHg in the aliskiren/HCTZ treated patients, compared to less than 21 mmHg among members of the HCTZ-only group, according to the news source.

Moreover, a total of 47 percent of participants who were on the dual medication regimen achieved the target blood pressure of less than 140/90 by the end of the four weeks, as opposed to only 34 percent of those who took one drug for hypertension.

The American Diabetes Association states that as many as 2 out of every three people with type 1 diabetes or type 2 diabetes have high blood pressure. However, the organization notes that individuals who have their blood pressure checked regularly and make healthy lifestyle changes to reach a goal reading of 130/80 may be able to avoid complications related to diabetes and hypertension.
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