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Researchers look to delve deeper into common type 2 diabetes surgery phenomenon

There is a phenomenon out there for type 2 diabetes patients who undergo metabolic surgery and suddenly recover from their condition before they even begin to lose weight. While this is a good side effect, scientists are looking to determine the cause of this event.

Researchers at the Lund University Diabetes Center are trying to learn about this phenomenon to better understand the condition so that they may be able to provide non-surgical treatment options to diabetic patients. The researchers zeroed in on a side effect that occurs in 85 percent of diabetic patients receiving the treatment, where a fast normalization of the glucose homeostasis occurs.

"We don't mean that everyone with type 2 diabetes should undergo surgery, but maybe we can learn to achieve the same anti-diabetic effect without the surgery," said researcher Nils Wierup.



The study's authors observed both diabetic patients and pigs who had received the metabolic surgery, noting that pigs were suitable because they resembled humans in an anatomical way.

The scientists noted that the changes in the effect of gastrointestinal hormones may be the cause of this outcome. They were quick to point out that while gastric bypass surgery changes the conditions of the gastrointestinal tract, metabolic surgery could change the gastrointestinal bacterial floral due to the pH changes.

Additionally, the study's scientists noted that further research could also find that a less extensive gastric bypass surgery could still have the same effect, and if that were the case they would need to search a smaller area.

Still, the researchers were quick to point out that more studies must be done in order to better understand this side effect in an effort to create further, non-invasive treatments down the line.
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